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Uncoupling global and fine-tuning replication timing determinants for mouse pericentric heterochromatin
Mouse chromocenters are clusters of late-replicating pericentric heterochromatin containing HP1 bound to trimethylated lysine 9 of histone H3 (Me(3)K9H3). Using a cell-free system to initiate replication within G1-phase nuclei, we demonstrate that chromocenters acquire the property of late replicati...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064179/ https://www.ncbi.nlm.nih.gov/pubmed/16831888 http://dx.doi.org/10.1083/jcb.200601113 |