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Condensin I recruitment and uneven chromatin condensation precede mitotic cell death in response to DNA damage

Mitotic cell death (MCD) is a prominent but poorly defined form of death that stems from aberrant mitosis. One of the early steps in MCD is premature mitosis and uneven chromatin condensation (UCC). The mechanism underlying this phenomenon is currently unknown. In this study, we show that DNA damage...

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Detalles Bibliográficos
Autores principales: Blank, Michael, Lerenthal, Yaniv, Mittelman, Leonid, Shiloh, Yosef
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064180/
https://www.ncbi.nlm.nih.gov/pubmed/16847100
http://dx.doi.org/10.1083/jcb.200604022