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Complete repair of dystrophic skeletal muscle by mesoangioblasts with enhanced migration ability

Efficient delivery of cells to target tissues is a major problem in cell therapy. We report that enhancing delivery of mesoangioblasts leads to a complete reconstitution of downstream skeletal muscles in a mouse model of severe muscular dystrophy (α-sarcoglycan ko). Mesoangioblasts, vessel-associate...

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Detalles Bibliográficos
Autores principales: Galvez, Beatriz G., Sampaolesi, Maurilio, Brunelli, Silvia, Covarello, Diego, Gavina, Manuela, Rossi, Barbara, Costantin, Gabriela, Torrente, Yvan, Cossu, Giulio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064183/
https://www.ncbi.nlm.nih.gov/pubmed/16831885
http://dx.doi.org/10.1083/jcb.200512085