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α-Herpesvirus glycoprotein D interaction with sensory neurons triggers formation of varicosities that serve as virus exit sites

α-Herpesviruses constitute closely related neurotropic viruses, including herpes simplex virus in man and pseudorabies virus (PRV) in pigs. Peripheral sensory neurons, such as trigeminal ganglion (TG) neurons, are predominant target cells for virus spread and lifelong latent infections. We report th...

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Detalles Bibliográficos
Autores principales: De Regge, Nick, Nauwynck, Hans J., Geenen, Kristin, Krummenacher, Claude, Cohen, Gary H., Eisenberg, Roselyn J., Mettenleiter, Thomas C., Favoreel, Herman W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064186/
https://www.ncbi.nlm.nih.gov/pubmed/16831884
http://dx.doi.org/10.1083/jcb.200510156