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BDNF mobilizes synaptic vesicles and enhances synapse formation by disrupting cadherin–β-catenin interactions

Neurons of the vertebrate central nervous system have the capacity to modify synapse number, morphology, and efficacy in response to activity. Some of these functions can be attributed to activity-induced synthesis and secretion of the neurotrophin brain-derived neurotrophic factor (BDNF); however,...

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Detalles Bibliográficos
Autores principales: Bamji, Shernaz X., Rico, Beatriz, Kimes, Nikole, Reichardt, Louis F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064188/
https://www.ncbi.nlm.nih.gov/pubmed/16831887
http://dx.doi.org/10.1083/jcb.200601087