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The budding yeast PP2A(Cdc55) protein phosphatase prevents the onset of anaphase in response to morphogenetic defects
Faithful chromosome transmission requires establishment of sister chromatid cohesion during S phase, followed by its removal at anaphase onset. Sister chromatids are tethered together by cohesin, which is displaced from chromosomes through cleavage of its Mcd1 subunit by the separase protease. Separ...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064206/ https://www.ncbi.nlm.nih.gov/pubmed/17502422 http://dx.doi.org/10.1083/jcb.200609088 |