Bim(S)-induced apoptosis requires mitochondrial localization but not interaction with anti-apoptotic Bcl-2 proteins

Release of apoptogenic proteins such as cytochrome c from mitochondria is regulated by pro- and anti-apoptotic Bcl-2 family proteins, with pro-apoptotic BH3-only proteins activating Bax and Bak. Current models assume that apoptosis induction occurs via the binding and inactivation of anti-apoptotic...

Descripción completa

Detalles Bibliográficos
Autores principales: Weber, Arnim, Paschen, Stefan A., Heger, Klaus, Wilfling, Florian, Frankenberg, Tobias, Bauerschmitt, Heike, Seiffert, Barbara M., Kirschnek, Susanne, Wagner, Hermann, Häcker, Georg
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064208/
https://www.ncbi.nlm.nih.gov/pubmed/17517961
http://dx.doi.org/10.1083/jcb.200610148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064208/
https://www.ncbi.nlm.nih.gov/pubmed/17517961
http://dx.doi.org/10.1083/jcb.200610148

Ejemplares similares