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GPI-anchored receptor clusters transiently recruit Lyn and Gα for temporary cluster immobilization and Lyn activation: single-molecule tracking study 1

The signaling mechanisms for glycosylphosphatidylinositol-anchored receptors (GPI-ARs) have been investigated by tracking single molecules in living cells. Upon the engagement or colloidal gold–induced cross-linking of CD59 (and other GPI-ARs) at physiological levels, CD59 clusters containing three...

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Detalles Bibliográficos
Autores principales: Suzuki, Kenichi G.N., Fujiwara, Takahiro K., Sanematsu, Fumiyuki, Iino, Ryota, Edidin, Michael, Kusumi, Akihiro
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064216/
https://www.ncbi.nlm.nih.gov/pubmed/17517964
http://dx.doi.org/10.1083/jcb.200609174