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GPI-anchored receptor clusters transiently recruit Lyn and Gα for temporary cluster immobilization and Lyn activation: single-molecule tracking study 1
The signaling mechanisms for glycosylphosphatidylinositol-anchored receptors (GPI-ARs) have been investigated by tracking single molecules in living cells. Upon the engagement or colloidal gold–induced cross-linking of CD59 (and other GPI-ARs) at physiological levels, CD59 clusters containing three...
Autores principales: | Suzuki, Kenichi G.N., Fujiwara, Takahiro K., Sanematsu, Fumiyuki, Iino, Ryota, Edidin, Michael, Kusumi, Akihiro |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064216/ https://www.ncbi.nlm.nih.gov/pubmed/17517964 http://dx.doi.org/10.1083/jcb.200609174 |
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