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Identification of Golgi-localized acyl transferases that palmitoylate and regulate endothelial nitric oxide synthase

Lipid modifications mediate the subcellular localization and biological activity of many proteins, including endothelial nitric oxide synthase (eNOS). This enzyme resides on the cytoplasmic aspect of the Golgi apparatus and in caveolae and is dually acylated by both N-myristoylation and S-palmitoyla...

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Detalles Bibliográficos
Autores principales: Fernández-Hernando, Carlos, Fukata, Masaki, Bernatchez, Pascal N., Fukata, Yuko, Lin, Michelle I., Bredt, David S., Sessa, William C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064233/
https://www.ncbi.nlm.nih.gov/pubmed/16864653
http://dx.doi.org/10.1083/jcb.200601051