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Identification of Golgi-localized acyl transferases that palmitoylate and regulate endothelial nitric oxide synthase
Lipid modifications mediate the subcellular localization and biological activity of many proteins, including endothelial nitric oxide synthase (eNOS). This enzyme resides on the cytoplasmic aspect of the Golgi apparatus and in caveolae and is dually acylated by both N-myristoylation and S-palmitoyla...
Autores principales: | Fernández-Hernando, Carlos, Fukata, Masaki, Bernatchez, Pascal N., Fukata, Yuko, Lin, Michelle I., Bredt, David S., Sessa, William C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064233/ https://www.ncbi.nlm.nih.gov/pubmed/16864653 http://dx.doi.org/10.1083/jcb.200601051 |
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