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N-syndecan deficiency impairs neural migration in brain

N-syndecan (syndecan-3) is a transmembrane proteoglycan that is abundantly expressed in the major axonal pathways and in the migratory routes of the developing brain. When ligated by heparin-binding (HB) growth-associated molecule (GAM; pleiotrophin), N-syndecan mediates cortactin–Src kinase-depende...

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Detalles Bibliográficos
Autores principales: Hienola, Anni, Tumova, Sarka, Kulesskiy, Evgeny, Rauvala, Heikki
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064262/
https://www.ncbi.nlm.nih.gov/pubmed/16908672
http://dx.doi.org/10.1083/jcb.200602043