Cargando…
N-syndecan deficiency impairs neural migration in brain
N-syndecan (syndecan-3) is a transmembrane proteoglycan that is abundantly expressed in the major axonal pathways and in the migratory routes of the developing brain. When ligated by heparin-binding (HB) growth-associated molecule (GAM; pleiotrophin), N-syndecan mediates cortactin–Src kinase-depende...
Autores principales: | Hienola, Anni, Tumova, Sarka, Kulesskiy, Evgeny, Rauvala, Heikki |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064262/ https://www.ncbi.nlm.nih.gov/pubmed/16908672 http://dx.doi.org/10.1083/jcb.200602043 |
Ejemplares similares
-
The Two Thrombospondin Type I Repeat Domains of HB-GAM Display a Cooperative Function in N-syndecan Binding and Regulation of Synaptic Plasticity
por: Raulo, Erkki, et al.
Publicado: (2006) -
Heparan sulfate proteoglycan syndecan-3 is a novel receptor for GDNF, neurturin, and artemin
por: Bespalov, Maxim M., et al.
Publicado: (2011) -
HB-GAM (pleiotrophin) reverses inhibition of neural regeneration by the CNS extracellular matrix
por: Paveliev, Mikhail, et al.
Publicado: (2016) -
HMGB4 is expressed by neuronal cells and affects the expression of genes involved in neural differentiation
por: Rouhiainen, Ari, et al.
Publicado: (2016) -
Syndecan-1 Enhances Proliferation, Migration and Metastasis of HT-1080 Cells in Cooperation with Syndecan-2
por: Péterfia, Bálint, et al.
Publicado: (2012)