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Nodes of Ranvier and axon initial segments are ankyrin G–dependent domains that assemble by distinct mechanisms
Axon initial segments (AISs) and nodes of Ranvier are sites of action potential generation and propagation, respectively. Both domains are enriched in sodium channels complexed with adhesion molecules (neurofascin [NF] 186 and NrCAM) and cytoskeletal proteins (ankyrin G and βIV spectrin). We show th...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064285/ https://www.ncbi.nlm.nih.gov/pubmed/17548513 http://dx.doi.org/10.1083/jcb.200612012 |