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Nodes of Ranvier and axon initial segments are ankyrin G–dependent domains that assemble by distinct mechanisms

Axon initial segments (AISs) and nodes of Ranvier are sites of action potential generation and propagation, respectively. Both domains are enriched in sodium channels complexed with adhesion molecules (neurofascin [NF] 186 and NrCAM) and cytoskeletal proteins (ankyrin G and βIV spectrin). We show th...

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Detalles Bibliográficos
Autores principales: Dzhashiashvili, Yulia, Zhang, Yanqing, Galinska, Jolanta, Lam, Isabel, Grumet, Martin, Salzer, James L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064285/
https://www.ncbi.nlm.nih.gov/pubmed/17548513
http://dx.doi.org/10.1083/jcb.200612012