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Inhibition of centrosome protein assembly leads to p53-dependent exit from the cell cycle

Previous evidence has indicated that an intact centrosome is essential for cell cycle progress and that elimination of the centrosome or depletion of individual centrosome proteins prevents the entry into S phase. To investigate the molecular mechanisms of centrosome-dependent cell cycle progress, w...

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Detalles Bibliográficos
Autores principales: Srsen, Vlastimil, Gnadt, Nicole, Dammermann, Alexander, Merdes, Andreas
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064305/
https://www.ncbi.nlm.nih.gov/pubmed/16943179
http://dx.doi.org/10.1083/jcb.200606051