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Muscle aging is associated with compromised Ca(2+) spark signaling and segregated intracellular Ca(2+) release

Reduced homeostatic capacity for intracellular Ca(2+) ([Ca(2+)](i)) movement may underlie the progression of sarcopenia and contractile dysfunction during muscle aging. We report two alterations to Ca(2+) homeostasis in skeletal muscle that are associated with aging. Ca(2+) sparks, which are the ele...

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Detalles Bibliográficos
Autores principales: Weisleder, Noah, Brotto, Marco, Komazaki, Shinji, Pan, Zui, Zhao, Xiaoli, Nosek, Thomas, Parness, Jerome, Takeshima, Hiroshi, Ma, Jianjie
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064307/
https://www.ncbi.nlm.nih.gov/pubmed/16943181
http://dx.doi.org/10.1083/jcb.200604166