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The elementary unit of store-operated Ca(2+) entry: local activation of CRAC channels by STIM1 at ER–plasma membrane junctions

The activation of store-operated Ca(2+) entry by Ca(2+) store depletion has long been hypothesized to occur via local interactions of the endoplasmic reticulum (ER) and plasma membrane, but the structure involved has never been identified. Store depletion causes the ER Ca(2+) sensor stromal interact...

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Detalles Bibliográficos
Autores principales: Luik, Riina M., Wu, Minnie M., Buchanan, JoAnn, Lewis, Richard S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064336/
https://www.ncbi.nlm.nih.gov/pubmed/16966423
http://dx.doi.org/10.1083/jcb.200604015