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PKA-activated ApAF–ApC/EBP heterodimer is a key downstream effector of ApCREB and is necessary and sufficient for the consolidation of long-term facilitation

Long-term memory requires transcriptional regulation by a combination of positive and negative transcription factors. Aplysia activating factor (ApAF) is known to be a positive transcription factor that forms heterodimers with ApC/EBP and ApCREB2. How these heterodimers are regulated and how they pa...

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Detalles Bibliográficos
Autores principales: Lee, Jin-A, Lee, Sue-Hyun, Lee, Changhoon, Chang, Deok-Jin, Lee, Yong, Kim, Hyoung, Cheang, Ye-Hwang, Ko, Hyoung-Gon, Lee, Yong-Seok, Jun, Heejung, Bartsch, Dusan, Kandel, Eric R., Kaang, Bong-Kiun
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064337/
https://www.ncbi.nlm.nih.gov/pubmed/16966424
http://dx.doi.org/10.1083/jcb.200512066