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RLIP76 (RalBP1) is an R-Ras effector that mediates adhesion-dependent Rac activation and cell migration

The Ras family of small GTPases regulates cell proliferation, spreading, migration and apoptosis, and malignant transformation by binding to several protein effectors. One such GTPase, R-Ras, plays distinct roles in each of these processes, but to date, identified R-Ras effectors were shared with ot...

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Detalles Bibliográficos
Autores principales: Goldfinger, Lawrence E., Ptak, Celeste, Jeffery, Erin D., Shabanowitz, Jeffrey, Hunt, Donald F., Ginsberg, Mark H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064341/
https://www.ncbi.nlm.nih.gov/pubmed/16966426
http://dx.doi.org/10.1083/jcb.200603111