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Cytopathic effects of the cytomegalovirus-encoded apoptosis inhibitory protein vMIA

Replication of human cytomegalovirus (CMV) requires the expression of the viral mitochondria–localized inhibitor of apoptosis (vMIA). vMIA inhibits apoptosis by recruiting Bax to mitochondria, resulting in its neutralization. We show that vMIA decreases cell size, reduces actin polymerization, and i...

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Detalles Bibliográficos
Autores principales: Poncet, Delphine, Pauleau, Anne-Laure, Szabadkai, Gyorgy, Vozza, Angelo, Scholz, Sebastian R., Le Bras, Morgane, Brière, Jean-Jacques, Jalil, Abdelali, Le Moigne, Ronan, Brenner, Catherine, Hahn, Gabriele, Wittig, Ilka, Schägger, Hermann, Lemaire, Christophe, Bianchi, Katiuscia, Souquère, Sylvie, Pierron, Gerard, Rustin, Pierre, Goldmacher, Victor S., Rizzuto, Rosario, Palmieri, Ferdinando, Kroemer, Guido
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064390/
https://www.ncbi.nlm.nih.gov/pubmed/16982800
http://dx.doi.org/10.1083/jcb.200604069