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NCAM promotes assembly and activity-dependent remodeling of the postsynaptic signaling complex

The neural cell adhesion molecule (NCAM) regulates synapse formation and synaptic strength via mechanisms that have remained unknown. We show that NCAM associates with the postsynaptic spectrin-based scaffold, cross-linking NCAM with the N-methyl-d-aspartate (NMDA) receptor and Ca(2+)/calmodulin-dep...

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Detalles Bibliográficos
Autores principales: Sytnyk, Vladimir, Leshchyns'ka, Iryna, Nikonenko, Alexander G., Schachner, Melitta
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064397/
https://www.ncbi.nlm.nih.gov/pubmed/17000882
http://dx.doi.org/10.1083/jcb.200604145