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Regulation of secretory transport by protein kinase D–mediated phosphorylation of the ceramide transfer protein

Protein kinase D (PKD) has been identified as a crucial regulator of secretory transport at the trans-Golgi network (TGN). Recruitment and activation of PKD at the TGN is mediated by the lipid diacylglycerol, a pool of which is generated by sphingomyelin synthase from ceramide and phosphatidylcholin...

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Detalles Bibliográficos
Autores principales: Fugmann, Tim, Hausser, Angelika, Schöffler, Patrik, Schmid, Simone, Pfizenmaier, Klaus, Olayioye, Monilola A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064413/
https://www.ncbi.nlm.nih.gov/pubmed/17591919
http://dx.doi.org/10.1083/jcb.200612017