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Subcompartments of the macrophage recycling endosome direct the differential secretion of IL-6 and TNFα

Activated macrophages secrete an array of proinflammatory cytokines, including tumor necrosis factor-α (TNFα) and interleukin 6 (IL-6), that are temporally secreted for sequential roles in inflammation. We have previously characterized aspects of the intracellular trafficking of membrane-bound TNFα...

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Detalles Bibliográficos
Autores principales: Manderson, Anthony P., Kay, Jason G., Hammond, Luke A., Brown, Darren L., Stow, Jennifer L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064421/
https://www.ncbi.nlm.nih.gov/pubmed/17606866
http://dx.doi.org/10.1083/jcb.200612131