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Subcompartments of the macrophage recycling endosome direct the differential secretion of IL-6 and TNFα
Activated macrophages secrete an array of proinflammatory cytokines, including tumor necrosis factor-α (TNFα) and interleukin 6 (IL-6), that are temporally secreted for sequential roles in inflammation. We have previously characterized aspects of the intracellular trafficking of membrane-bound TNFα...
Autores principales: | Manderson, Anthony P., Kay, Jason G., Hammond, Luke A., Brown, Darren L., Stow, Jennifer L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064421/ https://www.ncbi.nlm.nih.gov/pubmed/17606866 http://dx.doi.org/10.1083/jcb.200612131 |
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