BMP gradients steer nerve growth cones by a balancing act of LIM kinase and Slingshot phosphatase on ADF/cofilin

Bone morphogenic proteins (BMPs) are involved in axon pathfinding, but how they guide growth cones remains elusive. In this study, we report that a BMP7 gradient elicits bidirectional turning responses from nerve growth cones by acting through LIM kinase (LIMK) and Slingshot (SSH) phosphatase to reg...

Descripción completa

Detalles Bibliográficos
Autores principales: Wen, Zhexing, Han, Liang, Bamburg, James R., Shim, Sangwoo, Ming, Guo-li, Zheng, James Q.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064427/
https://www.ncbi.nlm.nih.gov/pubmed/17606869
http://dx.doi.org/10.1083/jcb.200703055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064427/
https://www.ncbi.nlm.nih.gov/pubmed/17606869
http://dx.doi.org/10.1083/jcb.200703055

Ejemplares similares