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Locally controlled inhibitory mechanisms are involved in eukaryotic GPCR-mediated chemosensing

Gprotein–coupled receptor (GPCR) signaling mediates a balance of excitatory and inhibitory activities that regulate Dictyostelium chemosensing to cAMP. The molecular nature and kinetics of these inhibitors are unknown. We report that transient cAMP stimulations induce PIP(3) responses without a refr...

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Detalles Bibliográficos
Autores principales: Xu, Xuehua, Meier-Schellersheim, Martin, Yan, Jianshe, Jin, Tian
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064430/
https://www.ncbi.nlm.nih.gov/pubmed/17606871
http://dx.doi.org/10.1083/jcb.200611096