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Differential phosphorylation of NG2 proteoglycan by ERK and PKCα helps balance cell proliferation and migration
Two distinct Thr phosphorylation events within the cytoplasmic domain of the NG2 proteoglycan help regulate the cellular balance between proliferation and motility. Protein kinase Cα mediates the phosphorylation of NG2 at Thr(2256), resulting in enhanced cell motility. Extracellular signal–regulated...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064431/ https://www.ncbi.nlm.nih.gov/pubmed/17591920 http://dx.doi.org/10.1083/jcb.200612084 |