G protein–independent Ras/PI3K/F-actin circuit regulates basic cell motility

Phosphoinositide 3-kinase (PI3K)γ and Dictyostelium PI3K are activated via G protein–coupled receptors through binding to the Gβγ subunit and Ras. However, the mechanistic role(s) of Gβγ and Ras in PI3K activation remains elusive. Furthermore, the dynamics and function of PI3K activation in the abse...

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Detalles Bibliográficos
Autores principales: Sasaki, Atsuo T., Janetopoulos, Chris, Lee, Susan, Charest, Pascale G., Takeda, Kosuke, Sundheimer, Lauren W., Meili, Ruedi, Devreotes, Peter N., Firtel, Richard A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064438/
https://www.ncbi.nlm.nih.gov/pubmed/17635933
http://dx.doi.org/10.1083/jcb.200611138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064438/
https://www.ncbi.nlm.nih.gov/pubmed/17635933
http://dx.doi.org/10.1083/jcb.200611138

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