BUB1 mediation of caspase-independent mitotic death determines cell fate

The spindle checkpoint that monitors kinetochore–microtubule attachment has been implicated in tumorigenesis; however, the relation between the spindle checkpoint and cell death remains obscure. In BUB1-deficient (but not MAD2-deficient) cells, conditions that activate the spindle checkpoint (i.e.,...

Descripción completa

Detalles Bibliográficos
Autores principales: Niikura, Yohei, Dixit, Amruta, Scott, Ray, Perkins, Guy, Kitagawa, Katsumi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064447/
https://www.ncbi.nlm.nih.gov/pubmed/17620410
http://dx.doi.org/10.1083/jcb.200702134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064447/
https://www.ncbi.nlm.nih.gov/pubmed/17620410
http://dx.doi.org/10.1083/jcb.200702134

Ejemplares similares