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Type Iγ phosphatidylinositol phosphate kinase is required for EGF-stimulated directional cell migration
Phosphatidylinositol 4,5-bisphosphate (PI4,5P(2)) modulates a plethora of cytoskeletal interactions that control the dynamics of actin assembly and, ultimately, cell migration. We show that the type Iγ phosphatidylinositol phosphate kinase 661 (PIPKIγ661), an enzyme that generates PI4,5P(2), is requ...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064448/ https://www.ncbi.nlm.nih.gov/pubmed/17635937 http://dx.doi.org/10.1083/jcb.200701078 |