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Type Iγ phosphatidylinositol phosphate kinase is required for EGF-stimulated directional cell migration

Phosphatidylinositol 4,5-bisphosphate (PI4,5P(2)) modulates a plethora of cytoskeletal interactions that control the dynamics of actin assembly and, ultimately, cell migration. We show that the type Iγ phosphatidylinositol phosphate kinase 661 (PIPKIγ661), an enzyme that generates PI4,5P(2), is requ...

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Detalles Bibliográficos
Autores principales: Sun, Yue, Ling, Kun, Wagoner, Matthew P., Anderson, Richard A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064448/
https://www.ncbi.nlm.nih.gov/pubmed/17635937
http://dx.doi.org/10.1083/jcb.200701078