p32 is a novel mammalian Lgl binding protein that enhances the activity of protein kinase Cζ and regulates cell polarity

Lgl (lethal giant larvae) plays an important role in cell polarity. Atypical protein kinase C (aPKC) binds to and phosphorylates Lgl, and the phosphorylation negatively regulates Lgl activity. In this study, we identify p32 as a novel Lgl binding protein that directly binds to a domain on mammalian...

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Detalles Bibliográficos
Autores principales: Bialucha, Carl U., Ferber, Emma C., Pichaud, Franck, Peak-Chew, Sew Y., Fujita, Yasuyuki
Formato: Texto
Lenguaje:English
Publicado: Rockefeller University Press|1 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064465/
https://www.ncbi.nlm.nih.gov/pubmed/17682048
http://dx.doi.org/10.1083/jcb.200612022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064465/
https://www.ncbi.nlm.nih.gov/pubmed/17682048
http://dx.doi.org/10.1083/jcb.200612022

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