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Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium

The HMG-box transcription factor Sox9 is expressed in the intestinal epithelium, specifically, in stem/progenitor cells and in Paneth cells. Sox9 expression requires an active β-catenin–Tcf complex, the transcriptional effector of the Wnt pathway. This pathway is critical for numerous aspects of the...

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Detalles Bibliográficos
Autores principales: Bastide, Pauline, Darido, Charbel, Pannequin, Julie, Kist, Ralf, Robine, Sylvie, Marty-Double, Christiane, Bibeau, Frédéric, Scherer, Gerd, Joubert, Dominique, Hollande, Frédéric, Blache, Philippe, Jay, Philippe
Formato: Texto
Lenguaje:English
Publicado: Rockefeller University Press|1 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064470/
https://www.ncbi.nlm.nih.gov/pubmed/17698607
http://dx.doi.org/10.1083/jcb.200704152