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Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium
The HMG-box transcription factor Sox9 is expressed in the intestinal epithelium, specifically, in stem/progenitor cells and in Paneth cells. Sox9 expression requires an active β-catenin–Tcf complex, the transcriptional effector of the Wnt pathway. This pathway is critical for numerous aspects of the...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press|1
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064470/ https://www.ncbi.nlm.nih.gov/pubmed/17698607 http://dx.doi.org/10.1083/jcb.200704152 |