Cargando…

Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium

The HMG-box transcription factor Sox9 is expressed in the intestinal epithelium, specifically, in stem/progenitor cells and in Paneth cells. Sox9 expression requires an active β-catenin–Tcf complex, the transcriptional effector of the Wnt pathway. This pathway is critical for numerous aspects of the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bastide, Pauline, Darido, Charbel, Pannequin, Julie, Kist, Ralf, Robine, Sylvie, Marty-Double, Christiane, Bibeau, Frédéric, Scherer, Gerd, Joubert, Dominique, Hollande, Frédéric, Blache, Philippe, Jay, Philippe
Formato:	Texto
Lenguaje:	English
Publicado:	Rockefeller University Press\|1 2007
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064470/ https://www.ncbi.nlm.nih.gov/pubmed/17698607 http://dx.doi.org/10.1083/jcb.200704152

Ejemplares similares

RIP140 Represses Intestinal Paneth Cell Differentiation and Interplays with SOX9 Signaling in Colorectal Cancer
por: Gleizes, Antoine, et al.
Publicado: (2021)

Profiling spermatogenic failure in adult testes bearing Sox9-deficient Sertoli cells identifies genes involved in feminization, inflammation and stress
por: Lardenois, Aurélie, et al.
Publicado: (2010)

Genetic Ablation of Afadin Causes Mislocalization and Deformation of Paneth Cells in the Mouse Small Intestinal Epithelium
por: Tanaka-Okamoto, Miki, et al.
Publicado: (2014)

Treatments of Squamous Cell Cancer
por: Charbel, Darido
Publicado: (2020)

TSC2/mTORC1 signaling controls Paneth and goblet cell differentiation in the intestinal epithelium
por: Zhou, Y, et al.
Publicado: (2015)

Tumor necrosis factor mRNA localized to Paneth cells of normal murine intestinal epithelium by in situ hybridization
Publicado: (1990)

Small intestinal stem cell identity is maintained with functional Paneth cells in heterotopically grafted epithelium onto the colon
por: Fukuda, Masayoshi, et al.
Publicado: (2014)

Squamous Cell Carcinoma—A Summary of Novel Advances in Pathogenesis and Therapies
por: Khan, Imran, et al.
Publicado: (2022)

Paneth cells and necrotizing enterocolitis
por: Underwood, Mark A.
Publicado: (2012)

SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes
por: Blache, Philippe, et al.
Publicado: (2004)

Constitutive STAT5 activation regulates Paneth and Paneth-like cells to control Clostridium difficile colitis
por: Liu, Ruixue, et al.
Publicado: (2019)

PANETH CELL GRANULE OF MOUSE INTESTINE
por: Selzman, H. M., et al.
Publicado: (1962)

Paneth cells in intestinal physiology and pathophysiology
por: Gassler, Nikolaus
Publicado: (2017)

DeMISTifying Paneth Cell Maturation
por: Spatz, Lillian B., et al.
Publicado: (2019)

SOX9 is an atypical intestinal tumor suppressor controlling the oncogenic Wnt/ß-catenin signaling
por: Prévostel, Corinne, et al.
Publicado: (2016)

Long-Lived Epidermal Cancer-Initiating Cells
por: Youssef, Marina, et al.
Publicado: (2017)

The p53 Isoform Δ133p53β Promotes Cancer Stem Cell Potential
por: Arsic, Nikola, et al.
Publicado: (2015)

ZnT2-Mediated Zinc Import Into Paneth Cell Granules Is Necessary for Coordinated Secretion and Paneth Cell Function in Mice
por: Podany, Abigail B., et al.
Publicado: (2016)

Paneth Cells in Intestinal Homeostasis and Tissue Injury
por: Roth, Sabrina, et al.
Publicado: (2012)

The Paneth Cell: A Guardian of Gut Health
por: Manary, Mark
Publicado: (2016)

Paneth Cells during Viral Infection and Pathogenesis
por: Holly, Mayumi K., et al.
Publicado: (2018)

Stem Cells behind the Barrier
por: Cangkrama, Michael, et al.
Publicado: (2013)

Targeted Therapy Against the Cell of Origin in Cutaneous Squamous Cell Carcinoma
por: Goldie, Stephen J., et al.
Publicado: (2019)

PANETH AND GOBLET CELL RENEWAL IN MOUSE DUODENAL CRYPTS
por: Troughton, W. David, et al.
Publicado: (1969)

Paneth cells as a site of origin for intestinal inflammation
por: Adolph, Timon E., et al.
Publicado: (2013)

Impact of Paneth Cell Autophagy on Inflammatory Bowel Disease
por: Wang, Shu-Ling, et al.
Publicado: (2018)

Mist1 Expression Is Required for Paneth Cell Maturation
por: Dekaney, Christopher M., et al.
Publicado: (2019)

Paneth cell adenocarcinoma of the colon: A rare entity
por: Nihed, Abdessayed, et al.
Publicado: (2019)

The Paneth Cell: The Curator and Defender of the Immature Small Intestine
por: Lueschow, Shiloh R., et al.
Publicado: (2020)

Paneth cells as the origin of intestinal cancer in the context of inflammation
por: Verhagen, Mathijs P., et al.
Publicado: (2023)

Maintenance and turnover of Sox2(+) adult stem cells in the gustatory epithelium
por: Ohmoto, Makoto, et al.
Publicado: (2022)

Loss of Grainy Head-Like 1 Is Associated with Disruption of the Epidermal Barrier and Squamous Cell Carcinoma of the Skin
por: Mlacki, Michal, et al.
Publicado: (2014)

mTOR Signalling in Head and Neck Cancer: Heads Up
por: Tan, Fiona H., et al.
Publicado: (2019)

Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration
por: Barrionuevo, Francisco J, et al.
Publicado: (2016)

Paneth cell ablation induces neonatal necrotizing enterocolitis in mice
Publicado: (2012)

Neoplastic Paneth cells in the experimental murine carcinoma of the small intestine.
por: Kim, W. H., et al.
Publicado: (1990)

Mouse Paneth cell antimicrobial function is independent of Nod2
por: Shanahan, Michael T, et al.
Publicado: (2014)

Paneth cell α-defensins and enteric microbiota in health and disease
por: NAKAMURA, Kiminori, et al.
Publicado: (2015)

Plasticity of Paneth cells and their ability to regulate intestinal stem cells
por: Mei, Xianglin, et al.
Publicado: (2020)

An Update Review on the Paneth Cell as Key to Ileal Crohn's Disease
por: Wehkamp, Jan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_btphd84s4p6l1crr71ms00f0mj