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Src kinase activity and SH2 domain regulate the dynamics of Src association with lipid and protein targets

Src functions depend on its association with the plasma membrane and with specific membrane-associated assemblies. Many aspects of these interactions are unclear. We investigated the functions of kinase, SH2, and SH3 domains in Src membrane interactions. We used FRAP beam-size analysis in live cells...

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Detalles Bibliográficos
Autores principales: Shvartsman, Dmitry E., Donaldson, John C., Diaz, Begoña, Gutman, Orit, Martin, G. Steven, Henis, Yoav I.
Formato: Texto
Lenguaje:English
Publicado: Rockefeller University Press|1 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064473/
https://www.ncbi.nlm.nih.gov/pubmed/17698610
http://dx.doi.org/10.1083/jcb.200701133