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Activation of NMDA receptors promotes dendritic spine development through MMP-mediated ICAM-5 cleavage

Matrix metalloproteinase (MMP)-2 and -9 are pivotal in remodeling many tissues. However, their functions and candidate substrates for brain development are poorly characterized. Intercellular adhesion molecule-5 (ICAM-5; Telencephalin) is a neuronal adhesion molecule that regulates dendritic elongat...

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Detalles Bibliográficos
Autores principales: Tian, Li, Stefanidakis, Michael, Ning, Lin, Van Lint, Philippe, Nyman-Huttunen, Henrietta, Libert, Claude, Itohara, Shigeyoshi, Mishina, Masayoshi, Rauvala, Heikki, Gahmberg, Carl G.
Formato: Texto
Lenguaje:English
Publicado: Rockefeller University Press|1 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064474/
https://www.ncbi.nlm.nih.gov/pubmed/17682049
http://dx.doi.org/10.1083/jcb.200612097