Cargando…

CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling

Integrin-dependent assembly of the fibronectin (Fn) matrix plays a central role in vertebrate development. We identify CD98hc, a membrane protein, as an important component of the matrix assembly machinery both in vitro and in vivo. CD98hc was not required for biosynthesis of cellular Fn or the main...

Descripción completa

Detalles Bibliográficos
Autores principales: Féral, Chloé C., Zijlstra, Andries, Tkachenko, Eugene, Prager, Gerald, Gardel, Margaret L., Slepak, Marina, Ginsberg, Mark H.
Formato: Texto
Lenguaje:English
Publicado: Rockefeller University Press|1 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064475/
https://www.ncbi.nlm.nih.gov/pubmed/17682053
http://dx.doi.org/10.1083/jcb.200705090