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CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling
Integrin-dependent assembly of the fibronectin (Fn) matrix plays a central role in vertebrate development. We identify CD98hc, a membrane protein, as an important component of the matrix assembly machinery both in vitro and in vivo. CD98hc was not required for biosynthesis of cellular Fn or the main...
Autores principales: | Féral, Chloé C., Zijlstra, Andries, Tkachenko, Eugene, Prager, Gerald, Gardel, Margaret L., Slepak, Marina, Ginsberg, Mark H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press|1
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064475/ https://www.ncbi.nlm.nih.gov/pubmed/17682053 http://dx.doi.org/10.1083/jcb.200705090 |
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