Cargando…

Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells

We report the interactions amongst 20 proteins that specify their assembly to the centromere–kinetochore complex in human cells. Centromere protein (CENP)-A is at the top of a hierarchy that directs three major pathways, which are specified by CENP-C, -I, and Aurora B. Each pathway consists of branc...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Song-Tao, Rattner, Jerome B., Jablonski, Sandra A., Yen, Tim J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064494/
https://www.ncbi.nlm.nih.gov/pubmed/17030981
http://dx.doi.org/10.1083/jcb.200606020