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BMP1 controls TGFβ1 activation via cleavage of latent TGFβ-binding protein
Transforming growth factor β1 (TGFβ1), an important regulator of cell behavior, is secreted as a large latent complex (LLC) in which it is bound to its cleaved prodomain (latency-associated peptide [LAP]) and, via LAP, to latent TGFβ-binding proteins (LTBPs). The latter target LLCs to the extracellu...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064503/ https://www.ncbi.nlm.nih.gov/pubmed/17015622 http://dx.doi.org/10.1083/jcb.200606058 |