Rapidly inducible changes in phosphatidylinositol 4,5-bisphosphate levels influence multiple regulatory functions of the lipid in intact living cells

Rapamycin (rapa)-induced heterodimerization of the FRB domain of the mammalian target of rapa and FKBP12 was used to translocate a phosphoinositide 5-phosphatase (5-ptase) enzyme to the plasma membrane (PM) to evoke rapid changes in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P (2)) levels. Ra...

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Detalles Bibliográficos
Autores principales: Varnai, Peter, Thyagarajan, Baskaran, Rohacs, Tibor, Balla, Tamas
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064515/
https://www.ncbi.nlm.nih.gov/pubmed/17088424
http://dx.doi.org/10.1083/jcb.200607116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064515/
https://www.ncbi.nlm.nih.gov/pubmed/17088424
http://dx.doi.org/10.1083/jcb.200607116

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