Cargando…

Shigella applies molecular mimicry to subvert vinculin and invade host cells

Shigella flexneri, the causative agent of bacillary dysentery, injects invasin proteins through a type III secretion apparatus upon contacting the host cell, which triggers pathogen internalization. The invasin IpaA is essential for S. flexneri pathogenesis and binds to the cytoskeletal protein vinc...

Descripción completa

Detalles Bibliográficos
Autores principales: Izard, Tina, Tran Van Nhieu, Guy, Bois, Philippe R.J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064523/
https://www.ncbi.nlm.nih.gov/pubmed/17088427
http://dx.doi.org/10.1083/jcb.200605091