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Two distinct arginine methyltransferases are required for biogenesis of Sm-class ribonucleoproteins

Small nuclear ribonucleoproteins (snRNPs) are core components of the spliceosome. The U1, U2, U4, and U5 snRNPs each contain a common set of seven Sm proteins. Three of these Sm proteins are posttranslationally modified to contain symmetric dimethylarginine (sDMA) residues within their C-terminal ta...

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Detalles Bibliográficos
Autores principales: Gonsalvez, Graydon B., Tian, Liping, Ospina, Jason K., Boisvert, François-Michel, Lamond, Angus I., Matera, A. Gregory
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064538/
https://www.ncbi.nlm.nih.gov/pubmed/17709427
http://dx.doi.org/10.1083/jcb.200702147