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Toll-like receptor 8 functions as a negative regulator of neurite outgrowth and inducer of neuronal apoptosis

Toll receptors in Drosophila melanogaster function in morphogenesis and host defense. Mammalian orthologues of Toll, the Toll-like receptors (TLRs), have been studied extensively for their essential functions in controlling innate and adaptive immune responses. We report that TLR8 is dynamically exp...

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Detalles Bibliográficos
Autores principales: Ma, Yinghua, Li, Jianxue, Chiu, Isaac, Wang, Yawen, Sloane, Jacob A., Lü, Jining, Kosaras, Bela, Sidman, Richard L., Volpe, Joseph J., Vartanian, Timothy
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064562/
https://www.ncbi.nlm.nih.gov/pubmed/17060494
http://dx.doi.org/10.1083/jcb.200606016