Defective mitochondrial peroxiredoxin-3 results in sensitivity to oxidative stress in Fanconi anemia

Cells from patients with Fanconi anemia (FA), an inherited disorder that includes bone marrow failure and cancer predisposition, have increased sensitivity to oxidative stress through an unknown mechanism. We demonstrate that the FA group G (FANCG) protein is found in mitochondria. Wild-type but not...

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Detalles Bibliográficos
Autores principales: Mukhopadhyay, Sudit S., Leung, Kathryn S., Hicks, M. John, Hastings, Philip J., Youssoufian, Hagop, Plon, Sharon E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064564/
https://www.ncbi.nlm.nih.gov/pubmed/17060495
http://dx.doi.org/10.1083/jcb.200607061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064564/
https://www.ncbi.nlm.nih.gov/pubmed/17060495
http://dx.doi.org/10.1083/jcb.200607061

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