Endosomes generate localized Rho–ROCK–MLC2–based contractile signals via Endo180 to promote adhesion disassembly

The regulated assembly and disassembly of focal adhesions and adherens junctions contributes to cell motility and tumor invasion. Pivotal in this process is phosphorylation of myosin light chain-2 (MLC2) by Rho kinase (ROCK) downstream of Rho activation, which generates the contractile force necessa...

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Detalles Bibliográficos
Autores principales: Sturge, Justin, Wienke, Dirk, Isacke, Clare M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064574/
https://www.ncbi.nlm.nih.gov/pubmed/17043135
http://dx.doi.org/10.1083/jcb.200602125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064574/
https://www.ncbi.nlm.nih.gov/pubmed/17043135
http://dx.doi.org/10.1083/jcb.200602125

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