Simple kinetic relationships and nonspecific competition govern nuclear import rates in vivo

Many cargoes destined for nuclear import carry nuclear localization signals that are recognized by karyopherins (Kaps). We present methods to quantitate import rates and measure Kap and cargo concentrations in single yeast cells in vivo, providing new insights into import kinetics. By systematically...

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Detalles Bibliográficos
Autores principales: Timney, Benjamin L., Tetenbaum-Novatt, Jaclyn, Agate, Diana S., Williams, Rosemary, Zhang, Wenzhu, Chait, Brian T., Rout, Michael P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064595/
https://www.ncbi.nlm.nih.gov/pubmed/17116750
http://dx.doi.org/10.1083/jcb.200608141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064595/
https://www.ncbi.nlm.nih.gov/pubmed/17116750
http://dx.doi.org/10.1083/jcb.200608141

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