The major human and mouse granzymes are structurally and functionally divergent

Approximately 2% of mammalian genes encode proteases. Comparative genomics reveals that those involved in immunity and reproduction show the most interspecies diversity and evidence of positive selection during evolution. This is particularly true of granzymes, the cytotoxic proteases of natural kil...

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Detalles Bibliográficos
Autores principales: Kaiserman, Dion, Bird, Catherina H., Sun, Jiuru, Matthews, Antony, Ung, Kheng, Whisstock, James C., Thompson, Philip E., Trapani, Joseph A., Bird, Phillip I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064598/
https://www.ncbi.nlm.nih.gov/pubmed/17116752
http://dx.doi.org/10.1083/jcb.200606073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064598/
https://www.ncbi.nlm.nih.gov/pubmed/17116752
http://dx.doi.org/10.1083/jcb.200606073

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