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Msk is required for nuclear import of TGF-β/BMP-activated Smads

Nuclear translocation of Smad proteins is a critical step in signal transduction of transforming growth factor β (TGF-β) and bone morphogenetic proteins (BMPs). Using nuclear accumulation of the Drosophila Smad Mothers against Decapentaplegic (Mad) as the readout, we carried out a whole-genome RNAi...

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Detalles Bibliográficos
Autores principales: Xu, Lan, Yao, Xiaohao, Chen, Xiaochu, Lu, Peiyuan, Zhang, Biliang, Ip, Y. Tony
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064622/
https://www.ncbi.nlm.nih.gov/pubmed/17785517
http://dx.doi.org/10.1083/jcb.200703106