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Katanin regulates dynamics of microtubules and biogenesis of motile cilia

The in vivo significance of microtubule severing and the mechanisms governing its spatial regulation are not well understood. In Tetrahymena, a cell type with elaborate microtubule arrays, we engineered null mutations in subunits of the microtubule-severing complex, katanin. We show that katanin act...

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Detalles Bibliográficos
Autores principales: Sharma, Neeraj, Bryant, Jessica, Wloga, Dorota, Donaldson, Rachel, Davis, Richard C., Jerka-Dziadosz, Maria, Gaertig, Jacek
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064628/
https://www.ncbi.nlm.nih.gov/pubmed/17846175
http://dx.doi.org/10.1083/jcb.200704021