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Kinesin-5 regulates the growth of the axon by acting as a brake on its microtubule array
Kinesin-5 is a homotetrameric motor protein that interacts with adjacent microtubules in the mitotic spindle. Kinesin-5 is also highly expressed in developing postmitotic neurons. Axons of cultured neurons experimentally depleted of kinesin-5 grow up to five times longer than controls and display mo...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064629/ https://www.ncbi.nlm.nih.gov/pubmed/17846176 http://dx.doi.org/10.1083/jcb.200702074 |